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Therefore, quantifying GSH in whole blood, as seen in the current study, provides an integrated measure of both intracellular and extracellular pools, offering a more physiologically relevant index of systemic glutathione availability

Homocysteine has been identified as a pathogenic feature of NAFLD in humans and alcoholic fatty liver disease in a rodent model

In addition, elevated levels of cell adhesion molecules (ICAM-1, VCAM-1, SELL, ITGB1, and ITGB2), NADPH oxidase activity, and inflammatory cytokines (MCP-1 and TNF) were observed in G6PD-deficient cells [10, 11] (Fig

M., Rashed, L